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Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas SAM-e is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.
SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAM-E metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.
Brain Metabolism
SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).
Liver
SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are components of the body's endogenous antioxidant network and important for liver function, including phase II detoxification.
EnteroGuard is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resist stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.
Servings per container: 20
Serving size: 1 tablet
Amount Per Tablet | % DV | |
S-Adenosyl Methionine (from 400 mg of SAM-e tosylate disulfate) | 200 mg | † |
† Daily Value not established.
Ingredients: Cellulose, glyceryl behenate, magnesium stearate (vegetable source), silicon dioxide, mannitol, sodium starch, glycolate an enteric coating (modified cellulose, magnesium silicate, triethyl citrate, and riboflavin. Suitable for vegetarians/vegans. No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts Full Potency 400 mg SAM-e (net yield) is derived from 800 mg of SAM-e tosylate disulfate.
Take 1 tablet 1 or 2 times per day on an empty stomach or as directed by your qualified healthcare professional. For best results, use with Jarrow Formulas JarroSil, the biologically Activated Silicon.
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Comments Jarrow Formulas Natural SAM-e S-Adenosyl-L-Methionine 200